| Week 1 | Top | |||
|---|---|---|---|---|
| Thursday, September 5 | Stadium | Surface | Location | Time |
| New York Giants at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 8:30pm |
| Sunday, September 8 | Stadium | Surface | Location | Time |
| Buffalo at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Carolina at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 1:00pm |
| Chicago at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 1:00pm |
| Cincinnati at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 1:00pm |
| Cleveland at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 1:00pm |
| Green Bay at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 1:00pm |
| Jacksonville at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 1:00pm |
| Miami at Detroit | Ford Field | FieldTurf | Detroit, MI | 1:00pm |
| Tennessee at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 1:00pm |
| Washington at Arizona | State Farm Stadium | Grass | Glendale, AZ | 1:00pm |
| Denver at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 4:15pm |
| Oakland at Seattle | Lumen Field | FieldTurf | Seattle, WA | 4:15pm |
| Tampa Bay at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 4:15pm |
| Houston at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 8:30pm |
| Monday, September 9 | Stadium | Surface | Location | Time |
| New England at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 9:15pm |
| Week 2 | Top | |||
|---|---|---|---|---|
| Sunday, September 15 | Stadium | Surface | Location | Time |
| Atlanta at Chicago | Soldier Field | Grass | Chicago, IL | 1:00pm |
| Baltimore at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 1:00pm |
| Carolina at Detroit | Ford Field | FieldTurf | Detroit, MI | 1:00pm |
| Cleveland at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 1:00pm |
| Dallas at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 1:00pm |
| Indianapolis at Miami | Hard Rock Stadium | Grass | Miami, FL | 1:00pm |
| Kansas City at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 1:00pm |
| New Orleans at Green Bay | Lambeau Field | Grass | Green Bay, WI | 1:00pm |
| New York Jets at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 1:00pm |
| St. Louis at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 3:05pm |
| Seattle at Arizona | State Farm Stadium | Grass | Glendale, AZ | 4:00pm |
| San Francisco at Denver | Empower Field at Mile High | Grass | Denver, CO | 4:00pm |
| Minnesota at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 4:15pm |
| San Diego at Houston | NRG Stadium | Grass | Houston, TX | 4:15pm |
| Pittsburgh at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 8:30pm |
| Monday, September 16 | Stadium | Surface | Location | Time |
| Washington at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 9:00pm |
| Week 3 | Top | |||
|---|---|---|---|---|
| Sunday, September 22 | Stadium | Surface | Location | Time |
| Chicago at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 1:00pm |
| Houston at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 1:00pm |
| Miami at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Minnesota at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 1:00pm |
| New England at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 1:00pm |
| Philadelphia at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 1:00pm |
| Tennessee at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 1:00pm |
| Arizona at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 4:00pm |
| Denver at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 4:00pm |
| Detroit at Green Bay | Lambeau Field | Grass | Green Bay, WI | 4:15pm |
| New York Giants at Seattle | Lumen Field | FieldTurf | Seattle, WA | 4:15pm |
| San Francisco at Washington | Northwest Stadium | Grass | Landover, MD | 4:15pm |
| Atlanta at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 8:30pm |
| Monday, September 23 | Stadium | Surface | Location | Time |
| Tampa Bay at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 9:00pm |
| Bye: BAL, JAC, OAK, PITBaltimore, Jacksonville, Oakland, Pittsburgh | ||||
| Week 4 | Top | |||
|---|---|---|---|---|
| Sunday, September 29 | Stadium | Surface | Location | Time |
| Buffalo at Chicago | Soldier Field | Grass | Chicago, IL | 1:00pm |
| Detroit at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 1:00pm |
| Green Bay at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 1:00pm |
| Jacksonville at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Kansas City at Miami | Hard Rock Stadium | Grass | Miami, FL | 1:00pm |
| Philadelphia at Houston | NRG Stadium | Grass | Houston, TX | 1:00pm |
| Pittsburgh at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 1:00pm |
| St. Louis at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 1:00pm |
| Arizona at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 4:00pm |
| Cincinnati at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 4:00pm |
| Oakland at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 4:15pm |
| San Diego at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 4:15pm |
| Seattle at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 8:30pm |
| Monday, September 30 | Stadium | Surface | Location | Time |
| Baltimore at Denver | Empower Field at Mile High | Grass | Denver, CO | 9:00pm |
| Bye: ATL, IND, SFO, WASAtlanta, Indianapolis, San Francisco, Washington | ||||
| Week 5 | Top | |||
|---|---|---|---|---|
| Sunday, October 6 | Stadium | Surface | Location | Time |
| Indianapolis at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 12:00pm |
| Atlanta at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 1:00pm |
| Buffalo at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 1:00pm |
| Carolina at Arizona | State Farm Stadium | Grass | Glendale, AZ | 1:00pm |
| Dallas at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Miami at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 1:00pm |
| New Orleans at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 1:00pm |
| Tennessee at Washington | Northwest Stadium | Grass | Landover, MD | 1:00pm |
| Denver at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 4:00pm |
| New York Jets at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 4:00pm |
| Jacksonville at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 4:15pm |
| San Francisco at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 4:15pm |
| Cleveland at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 8:30pm |
| Monday, October 7 | Stadium | Surface | Location | Time |
| Chicago at Green Bay | Lambeau Field | Grass | Green Bay, WI | 9:00pm |
| Bye: DET, HOU, MIN, SEADetroit, Houston, Minnesota, Seattle | ||||
| Week 6 | Top | |||
|---|---|---|---|---|
| Sunday, October 13 | Stadium | Surface | Location | Time |
| Indianapolis at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 12:00pm |
| Cincinnati at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 1:00pm |
| Dallas at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 1:00pm |
| Houston at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 1:00pm |
| Minnesota at Detroit | Ford Field | FieldTurf | Detroit, MI | 1:00pm |
| New England at Green Bay | Lambeau Field | Grass | Green Bay, WI | 1:00pm |
| New York Giants at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 1:00pm |
| Tampa Bay at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 1:00pm |
| Washington at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 1:00pm |
| Tennessee at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 4:00pm |
| San Diego at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 4:15pm |
| St. Louis at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 4:15pm |
| Denver at Miami | Hard Rock Stadium | Grass | Miami, FL | 8:30pm |
| Monday, October 14 | Stadium | Surface | Location | Time |
| Seattle at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 9:00pm |
| Bye: ARI, CHI, NYJ, PHIArizona, Chicago, New York Jets, Philadelphia | ||||
| Week 7 | Top | |||
|---|---|---|---|---|
| Sunday, October 20 | Stadium | Surface | Location | Time |
| Atlanta at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 1:00pm |
| Baltimore at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 1:00pm |
| Detroit at Chicago | Soldier Field | Grass | Chicago, IL | 1:00pm |
| Kansas City at Denver | Empower Field at Mile High | Grass | Denver, CO | 1:00pm |
| Miami at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 1:00pm |
| New Orleans at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 1:00pm |
| New York Jets at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 1:00pm |
| St. Louis at Seattle | Lumen Field | FieldTurf | Seattle, WA | 1:00pm |
| Cleveland at Houston | NRG Stadium | Grass | Houston, TX | 4:00pm |
| Oakland at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 4:00pm |
| Arizona at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 4:15pm |
| Green Bay at Washington | Northwest Stadium | Grass | Landover, MD | 4:15pm |
| Philadelphia at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 4:15pm |
| Monday, October 21 | Stadium | Surface | Location | Time |
| Pittsburgh at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 9:00pm |
| Bye: CIN, NWE, NYG, TENCincinnati, New England, New York Giants, Tennessee | ||||
| Week 8 | Top | |||
|---|---|---|---|---|
| Sunday, October 27 | Stadium | Surface | Location | Time |
| Baltimore at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 1:00pm |
| Buffalo at Detroit | Ford Field | FieldTurf | Detroit, MI | 1:00pm |
| Carolina at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 1:00pm |
| Cincinnati at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 1:00pm |
| Dallas at Seattle | Lumen Field | FieldTurf | Seattle, WA | 1:00pm |
| Kansas City at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 1:00pm |
| Minnesota at Chicago | Soldier Field | Grass | Chicago, IL | 1:00pm |
| New Orleans at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 1:00pm |
| New York Jets at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 1:00pm |
| San Francisco at Arizona | State Farm Stadium | Grass | Glendale, AZ | 4:00pm |
| Jacksonville at Houston | NRG Stadium | Grass | Houston, TX | 4:15pm |
| New England at Denver | Empower Field at Mile High | Grass | Denver, CO | 4:15pm |
| Washington at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 8:30pm |
| Monday, October 28 | Stadium | Surface | Location | Time |
| Philadelphia at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 9:00pm |
| Bye: GNB, MIA, SDG, STLGreen Bay, Miami, San Diego, St. Louis | ||||
| Week 9 | Top | |||
|---|---|---|---|---|
| Sunday, November 3 | Stadium | Surface | Location | Time |
| Atlanta at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 1:00pm |
| Buffalo at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 1:00pm |
| Chicago at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 1:00pm |
| Cleveland at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 1:00pm |
| Detroit at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 1:00pm |
| Houston at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 1:00pm |
| Indianapolis at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 1:00pm |
| Tampa Bay at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 1:00pm |
| San Diego at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 4:00pm |
| Arizona at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 4:15pm |
| Oakland at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 4:15pm |
| Seattle at Washington | Northwest Stadium | Grass | Landover, MD | 4:15pm |
| New York Giants at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 8:30pm |
| Monday, November 4 | Stadium | Surface | Location | Time |
| Green Bay at Miami | Hard Rock Stadium | Grass | Miami, FL | 9:00pm |
| Bye: CAR, DEN, KAN, NORCarolina, Denver, Kansas City, New Orleans | ||||
| Week 10 | Top | |||
|---|---|---|---|---|
| Sunday, November 10 | Stadium | Surface | Location | Time |
| Baltimore at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 1:00pm |
| Carolina at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 1:00pm |
| Green Bay at Detroit | Ford Field | FieldTurf | Detroit, MI | 1:00pm |
| Minnesota at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Philadelphia at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 1:00pm |
| Pittsburgh at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 1:00pm |
| St. Louis at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 1:00pm |
| Tennessee at Houston | NRG Stadium | Grass | Houston, TX | 1:00pm |
| Arizona at Seattle | Lumen Field | FieldTurf | Seattle, WA | 4:00pm |
| Jacksonville at Washington | Northwest Stadium | Grass | Landover, MD | 4:00pm |
| Chicago at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 4:15pm |
| San Francisco at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 4:15pm |
| New York Jets at Miami | Hard Rock Stadium | Grass | Miami, FL | 8:30pm |
| Monday, November 11 | Stadium | Surface | Location | Time |
| Denver at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 9:00pm |
| Bye: BUF, CLE, DAL, TAMBuffalo, Cleveland, Dallas, Tampa Bay | ||||
| Week 11 | Top | |||
|---|---|---|---|---|
| Sunday, November 17 | Stadium | Surface | Location | Time |
| Minnesota at Green Bay | Lambeau Field | Grass | Green Bay, WI | 12:00pm |
| Atlanta at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 1:00pm |
| Cincinnati at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 1:00pm |
| Houston at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 1:00pm |
| Indianapolis at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 1:00pm |
| Kansas City at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 1:00pm |
| New York Giants at Washington | Northwest Stadium | Grass | Landover, MD | 1:00pm |
| Philadelphia at Arizona | State Farm Stadium | Grass | Glendale, AZ | 1:00pm |
| Tennessee at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 1:00pm |
| San Diego at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 4:00pm |
| Tampa Bay at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 4:00pm |
| Detroit at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 4:15pm |
| Miami at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 4:15pm |
| Seattle at Denver | Empower Field at Mile High | Grass | Denver, CO | 4:15pm |
| Oakland at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 8:30pm |
| Monday, November 18 | Stadium | Surface | Location | Time |
| St. Louis at Chicago | Soldier Field | Grass | Chicago, IL | 9:00pm |
| Week 12 | Top | |||
|---|---|---|---|---|
| Sunday, November 24 | Stadium | Surface | Location | Time |
| Baltimore at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 1:00pm |
| Carolina at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 1:00pm |
| Chicago at Detroit | Ford Field | FieldTurf | Detroit, MI | 1:00pm |
| Dallas at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 1:00pm |
| Miami at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 1:00pm |
| New Orleans at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 1:00pm |
| New England at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 1:00pm |
| New York Jets at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 1:00pm |
| Pittsburgh at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 1:00pm |
| Washington at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 1:00pm |
| Arizona at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 4:00pm |
| Seattle at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 4:00pm |
| Houston at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 4:15pm |
| Tampa Bay at Green Bay | Lambeau Field | Grass | Green Bay, WI | 4:15pm |
| Denver at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 8:30pm |
| Monday, November 25 | Stadium | Surface | Location | Time |
| San Francisco at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 9:00pm |
| Week 13 | Top | |||
|---|---|---|---|---|
| Thursday, November 28 | Stadium | Surface | Location | Time |
| Detroit at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 12:38pm |
| Dallas at Washington | Northwest Stadium | Grass | Landover, MD | 4:15pm |
| Sunday, December 1 | Stadium | Surface | Location | Time |
| Minnesota at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 12:00pm |
| Buffalo at Miami | Hard Rock Stadium | Grass | Miami, FL | 1:00pm |
| Cincinnati at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 1:00pm |
| Cleveland at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 1:00pm |
| Green Bay at Chicago | Soldier Field | Grass | Chicago, IL | 1:00pm |
| Jacksonville at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 1:00pm |
| Kansas City at Arizona | State Farm Stadium | Grass | Glendale, AZ | 1:00pm |
| New York Giants at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 1:00pm |
| Indianapolis at Houston | NRG Stadium | Grass | Houston, TX | 4:00pm |
| San Diego at Denver | Empower Field at Mile High | Grass | Denver, CO | 4:00pm |
| Philadelphia at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 4:15pm |
| San Francisco at Seattle | Lumen Field | FieldTurf | Seattle, WA | 4:15pm |
| New Orleans at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 8:30pm |
| Monday, December 2 | Stadium | Surface | Location | Time |
| Oakland at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 9:00pm |
| Week 14 | Top | |||
|---|---|---|---|---|
| Sunday, December 8 | Stadium | Surface | Location | Time |
| Carolina at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 1:00pm |
| Dallas at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 1:00pm |
| Jacksonville at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 1:00pm |
| Kansas City at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 1:00pm |
| New England at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 1:00pm |
| Pittsburgh at Houston | NRG Stadium | Grass | Houston, TX | 1:00pm |
| Tampa Bay at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 1:00pm |
| Tennessee at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 1:00pm |
| Washington at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Arizona at Detroit | Ford Field | FieldTurf | Detroit, MI | 4:00pm |
| Baltimore at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 4:00pm |
| Seattle at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 4:00pm |
| New York Jets at Denver | Empower Field at Mile High | Grass | Denver, CO | 4:15pm |
| San Diego at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 4:15pm |
| Green Bay at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 8:30pm |
| Monday, December 9 | Stadium | Surface | Location | Time |
| Miami at Chicago | Soldier Field | Grass | Chicago, IL | 9:00pm |
| Week 15 | Top | |||
|---|---|---|---|---|
| Sunday, December 15 | Stadium | Surface | Location | Time |
| Atlanta at Seattle | Lumen Field | FieldTurf | Seattle, WA | 1:00pm |
| Buffalo at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 1:00pm |
| Chicago at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Cincinnati at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 1:00pm |
| Cleveland at Indianapolis | Lucas Oil Stadium | FieldTurf | Indianapolis, IN | 1:00pm |
| Detroit at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 1:00pm |
| Houston at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 1:00pm |
| Miami at Oakland | Oakland-Alameda County Coliseum | Grass | Oakland, CA | 1:00pm |
| New Orleans at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 1:00pm |
| Philadelphia at Washington | Northwest Stadium | Grass | Landover, MD | 1:00pm |
| Pittsburgh at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 1:00pm |
| Denver at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 4:00pm |
| New York Giants at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 4:15pm |
| San Francisco at Green Bay | Lambeau Field | Grass | Green Bay, WI | 4:15pm |
| St. Louis at Arizona | State Farm Stadium | Grass | Glendale, AZ | 8:30pm |
| Monday, December 16 | Stadium | Surface | Location | Time |
| Tennessee at New England | Gillette Stadium | FieldTurf | Foxborough, MA | 9:00pm |
| Week 16 | Top | |||
|---|---|---|---|---|
| Saturday, December 21 | Stadium | Surface | Location | Time |
| Minnesota at Miami | Hard Rock Stadium | Grass | Miami, FL | 1:00pm |
| Arizona at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 5:05pm |
| Dallas at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 8:30pm |
| Sunday, December 22 | Stadium | Surface | Location | Time |
| Atlanta at Detroit | Ford Field | FieldTurf | Detroit, MI | 1:00pm |
| Carolina at Chicago | Soldier Field | Grass | Chicago, IL | 1:00pm |
| Cincinnati at New Orleans | Caesars Superdome | Sportexe | New Orleans, LA | 1:00pm |
| Green Bay at Buffalo | Highmark Stadium | A-Turf Titan | Orchard Park, NY | 1:00pm |
| Indianapolis at New York Giants | MetLife Stadium | FieldTurf | East Rutherford, NJ | 1:00pm |
| Jacksonville at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 1:00pm |
| Kansas City at San Diego | Qualcomm Stadium | Grass | San Diego, CA | 1:00pm |
| Washington at Houston | NRG Stadium | Grass | Houston, TX | 1:00pm |
| Seattle at St. Louis | Edward Jones Dome | AstroTurf | St. Louis, MO | 4:00pm |
| Baltimore at Cleveland | FirstEnergy Stadium | Grass | Cleveland, OH | 4:15pm |
| Oakland at Denver | Empower Field at Mile High | Grass | Denver, CO | 4:15pm |
| New England at New York Jets | MetLife Stadium | FieldTurf | East Rutherford, NJ | 8:30pm |
| Monday, December 23 | Stadium | Surface | Location | Time |
| Tampa Bay at Pittsburgh | Acrisure Stadium | Grass | Pittsburgh, PA | 9:00pm |
| Week 17 | Top | |||
|---|---|---|---|---|
| Saturday, December 28 | Stadium | Surface | Location | Time |
| New York Giants at Philadelphia | Lincoln Financial Field | Grass | Philadelphia, PA | 1:00pm |
| Oakland at Kansas City | Arrowhead Stadium | Grass | Kansas City, MO | 5:15pm |
| Sunday, December 29 | Stadium | Surface | Location | Time |
| Buffalo at Cincinnati | Paycor Stadium | FieldTurf | Cincinnati, OH | 1:00pm |
| Cleveland at Atlanta | Mercedes-Benz Stadium | FieldTurf | Atlanta, GA | 1:00pm |
| Detroit at Minnesota | U.S. Bank Stadium | UBU Sports Speed | Minneapolis, MN | 1:00pm |
| Houston at Tennessee | Nissan Stadium | Matrix Helix Tur | Nashville, TN | 1:00pm |
| New Orleans at Carolina | Bank of America Stadium | FieldTurf | Charlotte, NC | 1:00pm |
| New England at Miami | Hard Rock Stadium | Grass | Miami, FL | 1:00pm |
| Pittsburgh at Baltimore | M&T Bank Stadium | Grass | Baltimore, MD | 1:00pm |
| Washington at Dallas | AT&T Stadium | RealGrass | Arlington, TX | 1:00pm |
| Indianapolis at Jacksonville | EverBank Stadium | Grass | Jacksonville, FL | 4:00pm |
| Denver at Arizona | State Farm Stadium | Grass | Glendale, AZ | 4:15pm |
| New York Jets at Green Bay | Lambeau Field | Grass | Green Bay, WI | 4:15pm |
| San Diego at Seattle | Lumen Field | FieldTurf | Seattle, WA | 4:15pm |
| Chicago at Tampa Bay | Raymond James Stadium | Grass | Tampa, FL | 8:30pm |
| Monday, December 30 | Stadium | Surface | Location | Time |
| St. Louis at San Francisco | Levi's Stadium | Grass | San Francisco, CA | 9:00pm |